Risperidonum [Latin]
Categoria
Risperidonum [Latin] Nombres de marca, Risperidonum [Latin] Analogos
Risperidonum [Latin] Marca los nombres de mezcla
Risperidonum [Latin] Formula quimica
C23H27FN4O2
Risperidonum [Latin] RX enlace
http://www.rxlist.com/cgi/generic/risperid.htm
Risperidonum [Latin] FDA hoja
Risperidonum [Latin] MSDS (hoja de seguridad de materiales)
Risperidonum [Latin] Sintesis de referencia
LEJ Kennis, J. Vandenberk, EE.UU. Pat. 4,804,663 (1989)
Risperidonum [Latin] Peso molecular
410.485 g/mol
Risperidonum [Latin] Punto de fusion
170oC
Risperidonum [Latin] H2O Solubilidad
2.8mg / L
Risperidonum [Latin] Estado
Solid
Risperidonum [Latin] LogP
2.718
Risperidonum [Latin] Formas de dosificacion
Tableta, solución (oral)
Risperidonum [Latin] Indicacion
Para el tratamiento de la esquizofrenia.
Risperidonum [Latin] Farmacologia
La risperidona es un medicamento antipsicótico atípico. Con mayor frecuencia se utiliza para tratar la psicosis delirante (como la esquizofrenia), pero risperidona también se utiliza para tratar algunas formas de trastorno bipolar y depresión psicótica. También se ha demostrado cierto éxito en el tratamiento de los síntomas del síndrome de Asperger y el autismo. La risperidona es ahora el medicamento antipsicótico más comúnmente recetados en los Estados Unidos. .
Risperidonum [Latin] Absorcion
Se absorbe bien. La biodisponibilidad oral absoluta de risperidona es del 70% (CV = 25%). La biodisponibilidad relativa de la risperidona oral de un comprimido es del 94% (CV = 10%) en comparación con una solución.
Risperidonum [Latin] Toxicidad
Los síntomas de sobredosis incluyen somnolencia, sedación, taquicardia, hipotensión y síntomas extrapiramidales. LD50 = 82.1mg/kg (por vía oral en ratones).
Risperidonum [Latin] Informacion de Pacientes
PATIENT INFORMATION
Physicians are advised to discuss the following issues with patients for whom they prescribe RISPERDAL�:
Orthostatic Hypotension
Patients should be advised of the risk of orthostatic hypotension, especially during the period of initial
dose titration.
Interference With Cognitive and Motor Performance
Since RISPERDAL� has the potential toimpair judgment, thinking, or motor skills, patients should be cautioned
about operating hazardous machinery, including automobiles, until they are reasonably certain that RISPERDAL�
therapy does not affect them adversely.
Pregnancy
Patients should be advised to notify their physician if they become pregnant or intend to become pregnant during
therapy.
Nursing
Patients should be advised not to breast-feed an infant if they are taking RISPERDAL.
Physicians are advised to discuss the following issues with patients for whom they prescribe RISPERDAL�:
Orthostatic Hypotension
Patients should be advised of the risk of orthostatic hypotension, especially during the period of initial
dose titration.
Interference With Cognitive and Motor Performance
Since RISPERDAL� has the potential toimpair judgment, thinking, or motor skills, patients should be cautioned
about operating hazardous machinery, including automobiles, until they are reasonably certain that RISPERDAL�
therapy does not affect them adversely.
Pregnancy
Patients should be advised to notify their physician if they become pregnant or intend to become pregnant during
therapy.
Nursing
Patients should be advised not to breast-feed an infant if they are taking RISPERDAL.
Risperidonum [Latin] Organismos afectados
Humanos y otros mamíferos
